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necrosis

noun

Simple meaning

The localized death of living cells.

Pronunciation

Say it like this:

nuhkrohsuhs

Say the bold part a little louder.

US device voice
IPA pronunciation (US)

nəkˈɹoʊsəs

This word is pronounced essentially the same in American and British English, so one transcription covers both.

IPA (International Phonetic Alphabet) is a standard way of writing speech sounds.

Word Review

Definition

Everyday modern meanings first, grouped by part of speech.

noun

  1. pathology

    The localized death of living cells (as from infection or the interruption of blood supply)

  2. pathology

    The localized death of cells or tissues through injury, disease, or the interruption of blood supply.

Word at a Glance

Difficulty
C1 · Advanced
Frequency
Uncommon
Typical Use
Neutral / general English

Word Aura™

How this word commonly comes across.

This meaning: The localized death of living cells (as from infection or the interruption of blood supply)

Used this way, necrosis is a specialist word with a clearly unfavourable pull. This is a clinical use: it belongs to medical description, where it is factual rather than emotive.

Emotional tone
Negative
Formality
Specialist/technical
Intensity
Moderate
How common
Specialized
Connotation
Serious and weighty
Usage feel
Clinical and detached

Where it naturally appears

  • Medicine/healthcare
  • Science
  • Technical/specialist writing

Usage note

In general conversation this sense usually needs explaining — outside its field, people reach for a plainer word.

Word Aura describes common impressions, not a measurement. Tone changes with sentence, speaker, relationship and situation.

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Common Patterns and Combinations

How this word naturally appears with others.

avascular necrosisfat necrosisnecrosis factortumor necrosistissue necrosishepatic necrosistumour necrosiscell necrosis

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Word Family

Related forms, grouped by how they connect.

Compound terms

Established multiword terms.

  • mumification necrosisnounCompound term

    Gangrene that develops in the presence of arterial obstruction and is characterized by dryness of the dead tissue and a dark brown color.

  • A deadly form of gangrene usually caused by clostridium bacteria that produce toxins that cause tissue death.

  • tumor necrosis factornounCompound term

    A proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages).

  • tumour necrosis factornounCompound term

    A proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages).

Related Words

Connected to the same idea, not synonyms.

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Dictionary data from Wiktionary via the Free Dictionary API. Simple meanings, combinations and word intelligence are built from verified reference data, no AI is used to load this page.