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immunodeficiency

noun

Simple meaning

Immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced.

Pronunciation

Say it like this:

ihmyoonohdihfishuhnsee

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US device voice
IPA pronunciation (US)

ɪmjunoʊdɪˈfɪʃənsi

This word is pronounced essentially the same in American and British English, so one transcription covers both.

IPA (International Phonetic Alphabet) is a standard way of writing speech sounds.

Word Review

Definition

Everyday modern meanings first, grouped by part of speech.

noun

  1. Immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced

  2. A depletion in the body's natural immune system, or in some component of it.

Word Aura™

How this word commonly comes across.

This meaning: Immunological disorder in which some part of the body's immune system is inadequate and resistance to infectious diseases is reduced

Used this way, immunodeficiency is a specialist word with a clearly unfavourable pull. This is a clinical use: it belongs to medical description, where it is factual rather than emotive.

Emotional tone
Negative
Formality
Specialist/technical
Intensity
Gentle
How common
Specialized
Connotation
Serious and weighty
Usage feel
Clinical and detached

Where it naturally appears

  • Medicine/healthcare
  • Science
  • Technical/specialist writing

Usage note

In general conversation this sense usually needs explaining — outside its field, people reach for a plainer word.

Word Aura describes common impressions, not a measurement. Tone changes with sentence, speaker, relationship and situation.

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Dictionary data from Wiktionary via the Free Dictionary API. Simple meanings, combinations and word intelligence are built from verified reference data, no AI is used to load this page.