estradiol
noun
Simple meaning
A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol secreted chiefly by the ovaries of all vertebrates.
Pronunciation
Say it like this:
ehstraydeeuhlSay the bold part a little louder.
IPA pronunciation (US)
ˈɛstɹeɪdiəl
This word is pronounced essentially the same in American and British English, so one transcription covers both.
IPA (International Phonetic Alphabet) is a standard way of writing speech sounds.
Definition
Everyday modern meanings first, grouped by part of speech.
noun
American spellingbiochemistrypharmacology
A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C₁₈H₂₄O₂) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer.
The most powerful female hormone that occurs naturally; synthesized and used to treat estrogen deficiency and breast cancer
Word Aura™
How this word commonly comes across.
This meaning: (American spelling, biochemistry, pharmacology) A natural estrogenic hormone that is a phenolic alcohol estra-1,3,5-triene-3,17-diol (C₁₈H₂₄O₂) secreted chiefly by the ovaries of all vertebrates, that is a major and the most potent of the naturally occurring estrogens; the semisynthetic esterified compound is used medicinally to treat estrogen deficiency and breast cancer.
Used this way, estradiol is a specialist word with a clearly unfavourable pull. It turns up most in technical or specialist writing contexts.
- Emotional tone
- Negative
- Formality
- Specialist/technical
- Intensity
- Gentle
- How common
- Specialized
- Connotation
- Serious and weighty
- Usage feel
- Clinical and detached
Where it naturally appears
- Technical/specialist writing
Usage note
In general conversation this sense usually needs explaining — outside its field, people reach for a plainer word.
Word Aura describes common impressions, not a measurement. Tone changes with sentence, speaker, relationship and situation.
Share your sentence
Use This Word
See how this word sounds in a real sentence.
Ask Vocabaura
Understand the word your way.
What Does It Mean Here?
Words can change meaning depending on context.
Use it yourself
Knowing “estradiol” starts when you use it. Pick a next step, all free.
Dictionary data from Wiktionary via the Free Dictionary API. Simple meanings, combinations and word intelligence are built from verified reference data, no AI is used to load this page.